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Endocrine Abstracts

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ea0073oc13.5 | Oral Communications 13: Pituitary and Neuroendocrinology | ECE2021

Potential therapeutic role of somatostatin and cortistatin in prostate cancer

Gomez Jesus Perez , Sáez-Mart Prudencio , Jiménez-Vacas Juan M. , Herrero-Aguayo nez-Vacas> , Pedraza-Arévalo Sergio , Enrique Gómez-Gómez , León-González Antonio J. , Martínez-Fuentes Antonio J. , Castaño Antonio J. , Gahete Manuel D. , Luque Raúl M.

Somatostatin (SST), Cortistatin (CORT), Neuronostatin (NST) and their receptors [SST/CORT-receptors (sst1–5/sst5TMD4-TMD5) and NST-receptor (GPR107)] comprise a hormonal pleiotropic system involved in the regulation of multiple pathophysiological functions. Certain components of this system are dysregulated in endocrine-related cancers, including prostate cancer (PCa), wherein we have found that alterations in specific components of this regulatory system [i.e. NST-GPR10...
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Endocrine Abstracts
ISSN 1470-3947 (print) | ISSN 1479-6848 (online)
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